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  • Leflunomide is an immunomodulating agent used to treat certain immune-mediated conditions in cats and dogs. It is used off label (extra label) in veterinary medicine. Leflunomide comes in a tablet form that may be specially compounded into a liquid. Wear gloves when handling and do not handle if pregnant or nursing.

  • The femoral head is the ball part of the hip joint and if it develops necrosis or dies, it can no longer function properly. Necrosis is due to loss of the blood supply to the femoral head, which may be the result of a growth abnormality or trauma to the hip. It is a hereditary condition of small breed dogs. The most common clinical signs are slowly progressing hind limb lameness with a resulting inability to bear weight on the affected limb or both hind limbs. Diagnosis is made by radiographs of the hip joint. The treatment of choice is femoral head and neck ostectomy, which results in a good prognosis.

  • Leishmaniasis is a disease caused by a protozoan parasite transmitted by sandflies and is most commonly seen in the Mediterranean, Middle East, and South and Central America. It has been reported in some parts of the United States. Clinical signs include hard skin nodules, weakness, decreased appetite, vomiting, diarrhea, and more. Diagnosis is based on travel history, clinical signs, and diagnostic testing. The goal of treatment is to resolve clinical signs. Prognosis is guarded to grave depending on the severity of the disease.

  • This handout discusses lens luxation in dogs. The lens is the transparent structure within the eye that focuses light on the retina. Lens luxation is when the support ligaments of the lens weaken or break, causing the lens to dislocate from its normal position. The various types, clinical signs, heredity of the condition, diagnosis, treatment, and prognosis are outlined.

  • Lenticular sclerosis is the term for a bluish, transparent haze that develops in the lens of the eye in middle-aged to senior dogs. Vision does not appear to be significantly affected. While the exact mechanism is poorly understood, it appears that the lens gradually becomes denser or harder with age. There is no specific treatment for lenticular sclerosis, nor is treatment necessary.

  • Leptospirosis is a bacterial disease of dogs and other mammals that primarily affects the liver or kidneys. The bacteria (Leptospira) that cause leptospirosis thrive in water. Infected or recovered carrier dogs may act as a source of the infection. Antibiotics such as penicillin, ampicillin, and amoxicillin are reasonably effective against the acute stages of leptospirosis, if started early, although most affected dogs require intensive care in the veterinary hospital. This disease can be transmitted to humans.

  • Levetiracetam is given by mouth or injection and is used off label to treat seizures and epilepsy. Give as directed by your veterinarian. Common side effects include sleepiness and incoordination in dogs and decreased appetite, incoordination, drooling, and sleepiness in cats. Do not use levetiracetam in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Levothyroxine is thyroid hormone replacement given by mouth in the form of a tablet or capsule. It is used to treat hypothyroidism and its use in cats and certain exotic animals is off label. This medication should not be used in pets with certain heart conditions, untreated Addison's disease, or hyperthyroidism.

  • Lick granuloma in dogs, also known as acral lick dermatitis, is a condition manifested as chronic licking of an area of skin, usually on the forelimbs. This condition is thought to be both physical and psychological in nature. While the condition can be frustrating to get under control, most cases of lick granulomas can be successfully treated if the owner is willing to pursue extended tests and treatments.

  • Lidocaine/lidocaine combinations topical are local anesthetics that provide anesthesia (a numbing effect) to the skin in cats, dogs, and other animals. Combination products may contain other local anesthetics, antibiotics or antimicrobials, steroids, antihistamines, and/or cleansing agents.